Marble Bones (Albers-Schonberg Disease)
نویسندگان
چکیده
منابع مشابه
Osteoclast-derived serum tartrate-resistant acid phosphatase 5b in Albers-Schonberg disease (type II autosomal dominant osteopetrosis).
BACKGROUND Albers-Schönberg disease, or autosomal dominant osteopetrosis type II (ADO2), is caused by ineffective osteoclastic bone resorption resulting from mutations in the chloride channel 7 (ClCN7) gene. Individuals with ADO2 have increased numbers of large ineffective osteoclasts in addition to increased serum total tartrate-resistant acid phosphatase (TRACP) activity. METHODS We investi...
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Osteopetrosis (OP) variably referred to as ‘Marble bone disease’ or ‘Albers Schonberg disease’ was first described by a German radiologist in 1904. It is a group of genetically and clinically heterogeneous disorders characterized by increased skeletal density. Clinical severity varies from asymptomatic adults to a life-threatening condition in infants. Autosomal recessive osteopetrosis has an i...
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Albers-Schönberg disease, or autosomal dominant osteopetrosis type II, is the most common form of the rare disease, osteopetrosis. Mandibular osteomyelitis is a rare complication of the disease. A host of other skeletal complications may also occur. Mandibular osteomyelitis along with bilateral severe coxa vara and pars fracture is very rare in Albers-Schönberg disease. We present the occurrenc...
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Two outbreaks of marble spleen disease were observed in pen-raised pheasants in Ontario on the same farm in the summer of 1971 and in 1972. In both instances, a mortality of 3% per day lasted for approximately 14 days. Fifteen birds were necropsied and tissues removed and examined histologically and by electron microscopy. In addition splenic material was injected into adult pheasants. The gros...
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Osteopetrosis is a rare metabolic disease.(1) Dental abnormalities may be attributed to the pathological changes in osteopetrosis. Patients with osteopetrosis are especially susceptible to osteomyelitis of mandible.(1) A 13-year-old girl presented with complaint of jaw swelling on left side. The radiograph of left mandible (lateral oblique view) showed small sequestrum with irregularity and ero...
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ژورنال
عنوان ژورنال: Proceedings of the Royal Society of Medicine
سال: 1931
ISSN: 0035-9157
DOI: 10.1177/003591573102500215